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A study by a research group at the Department of Physical Chemistry, University of Murcia on the combined effect of stacking and hydration in the spontaneous mutation in DNA is the cover of latest issue of the journal Physical Chemistry Chemical Physics, edited by the Royal Society of Chemistry.
Teachers Cerón José Pedro Carrasco, Jose Zuniga and Alberto Requena, the group lasers, molecular spectroscopy and quantum chemistry, in collaboration with other Belgian and French researchers, their findings prove that the combination of base pairs and disrupts the water molecules the mechanism of double proton transfer, and this is the basis of the explanation of spontaneous mutations in DNA.
On the one hand, they conclude, stacking and hydration greatly affect the geometry of base pairs and other, nearby water molecules play an active role in catalyzing proton transfer reaction.
The journal Physical Chemistry Chemical Physics is one of the most important publications in the field of atomic and molecular physics.
Source: Universidad de Murcia
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