Portal de Murcia
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The Research Group "Regeneration and repair of tissues: Orthobiology, Biomaterials and Tissue Engineering" led by Dr. Luis Meseguer Olmo of the UCAM, initiates a new R & D project, "Production and evaluation of the biological response Of high performance silk fibers: assessment of the biological response ", funded by the Ministry of Economy and Competitiveness, to regenerate cruciate ligaments using fibers obtained from the silk cocoon.
For three years this group of researchers from the Catholic University of Murcia together with Dr. José Pérez Rigueiro from the Biomedical Technology Center of the Polytechnic University of Madrid and Dr. José Luis Cenis from the Murciano Institute for Agricultural and Food Research and Development (IMIDA), are going to maintain a collaboration with the aim of designing and fabricating structures similar to those of a cord made of braided silk filaments to obtain a structure that will replace the cruciate ligaments of the knee.
To do this, a new procedure called straining flow spinning (SFS), developed by the group, will be used.
The study will be developed in 3 phases.
A first in vitro test in which quality control will be performed to prove that the design meets the physical, chemical and mechanical properties optimum and similar to those of the human ligament.
The second part has a double objective: to study the adhesion of cultured cells in the material developed and, on the other hand, to study the biological response after its implantation in the knee of animals.
In the third phase, the results obtained in these tests will be analyzed.
Source: UCAM
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