Portal de Murcia

www.portaldemurcia.com

• Home
• Business
• Hotels
• Restaurants
• News
• Advertisement

The MiBioPath group of the UCAM, through its principal investigator, Dr. Vicente Navarro, director of the Chair of Human Microbiota and Infectious Diseases, has presented the first data obtained in the study of the intestinal microbiota in multiple sclerosis, in the X National Workshop held by the SEPYP on February 6-8 at the Congress Palace of the Alfredo Kraus Auditorium in Las Palmas de Gran Canaria.

In the work carried out by the research group, the composition of the gut microbiota of a selection of patients with relapsing and remitting active multiple sclerosis was analyzed and compared with that of family members or cohabitants as a control group.

During 36 months, patients were followed up in which relapses and new lesions produced in the central nervous system were recorded.

Diet and weight evolution were also registered, as well as the BMI.

All these data were analyzed by statistical tests and correlated with the composition of the intestinal microbiota.

The results showed a clear difference between the microbiota of patients with active multiple sclerosis and that of healthy controls.

Correlations of some genera and some families of microorganisms with worse prognoses of the disease were detected so that the composition of the intestinal microbiota and its analysis could act as a predictive factor of the evolution of multiple sclerosis.

During this scientific event in which numerous national and international health professionals present the latest advances in the area of ​​intestinal microbiota, the UCAM researcher, Eva Nuñez, was in charge of presenting the second communication of the MiBioPah group: "Alpha diversity study in patients with Clostridium difficile infection and asymptomatic carriers ".

The biotechnologist showed some of the results of the research carried out in the development of the doctoral thesis of D. Pedro Sánchez Pellicer, of the Doctoral Program in Health Sciences of the UCAM, in relation to the composition of the intestinal microbiota and the overgrowth of Clostridium difficile.

The research group hopes that future lines will allow the identification of the triggers of the transition to a symptomatic state of infection, which could be due to certain minority groups of protective bacteria or predisposing to infection, to factors related to the immune status of the individual or the own virulence of Clostridium difficile.

Source: UCAM